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Smart Pairings: What Works Better Together

Some nutrients work best when paired with the right partners. Select a supplement to see the key cofactors or absorption helpers that make it work better.

B-Complex

  • Works with Magnesium and Zinc in energy and enzyme reactions.
  • Take with food to improve absorption and reduce nausea.

Calcium

  • Combine with Vitamin D3 + K2 – directs calcium into bones.
  • Take away from Iron or Zinc for better absorption.
  • Split large doses into morning + evening.

CoQ10 (Ubiquinol)

  • Works synergistically with NMN for mitochondrial energy.
  • Combine with Magnesium Malate for fatigue support.
  • Take with meals containing fat for best absorption.

Iron

  • Pair with Vitamin C – improves uptake and reduces gut irritation.
  • Avoid Calcium, Zinc, or Coffee within two hours of dosing.
  • Take with a meal if stomach upset occurs.

Magnesium

  • Works with Vitamin B6 (P5P) – helps magnesium enter cells.
  • Supports Vitamin D3 activation in the liver and kidneys.
  • Take away from zinc or iron to prevent competition.

NAC + Glycine (GlyNAC)

  • Combine with Magnesium and B-Complex – supports detox and energy pathways.
  • Take away from food if tolerated for faster absorption.
  • Drink extra water to support clearance.

NMN

  • Combine with TMG (Trimethylglycine) – supports methylation balance.
  • Add CoQ10 (Ubiquinol) – boosts mitochondrial energy.
  • Take in the morning on an empty stomach for best results.

Omega-3 (Fish Oil or Krill Oil)

  • Most quality products already include Vitamin E (mixed tocopherols) or Astaxanthin to prevent oxidation.
  • Do not add extra Vitamin E unless advised — excess can affect Vitamin K balance.
  • Combine with Vitamin D3 for immune and anti-inflammatory synergy.
  • Always take with a meal containing fat.

Probiotics

  • Combine with Prebiotics (fibre / inulin) – feed healthy gut bacteria.
  • Take before meals for best survival rate.
  • Separate by 2 hours after antibiotics if applicable.

Selenium

  • Works with Vitamin E – supports antioxidant defence.
  • Combine with Zinc for thyroid and immune support.
  • Take with food to improve tolerance.

TMG (Trimethylglycine)

  • Pair with NMN or B12 / Folate – maintains methylation.
  • Take with breakfast for steady methyl donor support.

Vitamin C

  • Enhances Iron absorption when taken together.
  • Works with Zinc for immune and antioxidant support.
  • Split dose morning and afternoon for steady levels.

Vitamin D3

  • Pair with Vitamin K2 (MK-7) – directs calcium into bones, not soft tissue.
  • Pair with Magnesium – needed to activate Vitamin D in the body.
  • Take with a meal containing healthy fats to improve absorption.

Vitamin K2 (MK-7)

  • Works alongside Vitamin D3 – helps manage calcium properly.
  • Combine with Calcium only when Vitamin D3 is also present.
  • Take with dietary fat for best uptake.

Zinc

  • Pair with Copper (10:1 ratio) – prevents imbalance.
  • Combine with Vitamin C – supports immune function.
  • Avoid taking at the same time as Calcium or Iron.

Smart Pairings: What Works Better Together

Some nutrients work best when paired with the right partners. Select a supplement to see the key cofactors or absorption helpers that make it work better.

Vitamin D3

  • Pair with Vitamin K2 (MK-7) – directs calcium into bones, not soft tissue.
  • Pair with Magnesium – needed to activate Vitamin D in the body.
  • Take with a meal containing healthy fats to improve absorption.

Vitamin K2 (MK-7)

  • Works alongside Vitamin D3 – helps manage calcium properly.
  • Combine with Calcium only when Vitamin D3 is also present.
  • Take with dietary fat for best uptake.

Magnesium

  • Works with Vitamin B6 (P5P) – helps magnesium enter cells.
  • Supports Vitamin D3 activation in the liver and kidneys.
  • Take away from zinc or iron to prevent competition.

Zinc

  • Pair with Copper (10:1 ratio) – prevents imbalance.
  • Combine with Vitamin C – supports immune function.
  • Avoid taking at the same time as Calcium or Iron.

Vitamin C

  • Enhances Iron absorption when taken together.
  • Works with Zinc for immune and antioxidant support.
  • Split dose morning and afternoon for steady levels.

NMN

  • Combine with TMG (Trimethylglycine) – supports methylation balance.
  • Add CoQ10 (Ubiquinol) – boosts mitochondrial energy.
  • Take in the morning on an empty stomach for best results.

B-Complex

  • Works with Magnesium and Zinc in energy and enzyme reactions.
  • Take with food to improve absorption and reduce nausea.

Iron

  • Pair with Vitamin C – improves uptake and reduces gut irritation.
  • Avoid Calcium, Zinc, or Coffee within two hours of dosing.
  • Take with a meal if stomach upset occurs.

Calcium

  • Combine with Vitamin D3 + K2 – directs calcium into bones.
  • Take away from Iron or Zinc for better absorption.
  • Split large doses into morning + evening.

Omega-3 (Fish Oil or Krill Oil)

  • Most quality products already include Vitamin E (mixed tocopherols) or Astaxanthin to prevent oxidation.
  • Do not add extra Vitamin E unless advised — excess can affect Vitamin K balance.
  • Combine with Vitamin D3 for immune and anti-inflammatory synergy.
  • Always take with a meal containing fat.

Probiotics

  • Combine with Prebiotics (fibre / inulin) – feed healthy gut bacteria.
  • Take before meals for best survival rate.
  • Separate by 2 hours after antibiotics if applicable.

Selenium

  • Works with Vitamin E – supports antioxidant defence.
  • Combine with Zinc for thyroid and immune support.
  • Take with food to improve tolerance.

TMG (Trimethylglycine)

  • Pair with NMN or B12 / Folate – maintains methylation.
  • Take with breakfast for steady methyl donor support.

CoQ10 (Ubiquinol)

  • Works synergistically with NMN for mitochondrial energy.
  • Combine with Magnesium Malate for fatigue support.
  • Take with meals containing fat for best absorption.

NAC + Glycine (GlyNAC)

  • Combine with Magnesium and B-Complex – supports detox and energy pathways.
  • Take away from food if tolerated for faster absorption.
  • Drink extra water to support clearance.

Quick notes

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