Science Refrences

NMN (Nicotinamide Mononucleotide)

  1. The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation increases blood NAD⁺ concentrations and is safe and well tolerated.

Summary: This human study found that NMN supplementation safely raises NAD⁺ levels, which are linked to energy metabolism and cellular repair.

2.  Ingestion of β-nicotinamide mononucleotide increased blood NAD⁺, maintained walking speed, and improved sleep quality in older adults.

Summary: Older adults taking NMN showed improved energy, mobility, and sleep quality compared to placebo.

BPC-157 (Body Protection Compound-157)

3.  The stable gastric pentadecapeptide BPC-157: pleiotropic beneficial activity and its possible relevance to dopamine neurotransmitter activity.

Summary: Reviews multiple studies showing BPC-157’s regenerative and neuroprotective properties in gut, tendon, and brain tissue.

4. Stable Gastric Pentadecapeptide BPC-157 and wound healing.

Summary: Demonstrates accelerated wound healing, tissue regeneration, and angiogenesis effects in various animal models.

Vitamin D3

5.  Effects of vitamin D supplementation on COVID-19 related outcomes: a systematic review and meta-analysis.

Summary: Concludes that adequate vitamin D levels are associated with improved immune outcomes and reduced respiratory infections.

6.  Vitamin D and immune function.

Summary: Reviews how vitamin D modulates both innate and adaptive immunity and its link to reduced inflammation.

Magnesium

7.  The role of magnesium in neurological disorders.

Summary: Highlights magnesium’s involvement in neurotransmission and its benefits for sleep, anxiety, and depression.

8.  Magnesium supplementation and blood pressure: a meta-analysis of randomized controlled trials.

Summary: Shows that magnesium can modestly lower blood pressure, especially in people with low dietary intake.

KPV Peptide

9.  Anti-inflammatory and immunomodulatory actions of α-melanocyte stimulating hormone and its derivatives (including KPV).

Summary: Demonstrates KPV’s ability to reduce inflammation through melanocortin receptor activation and cytokine modulation.

10.  The tripeptide KPV has anti-inflammatory properties and protects epithelial barrier function.

Summary: Laboratory study showing KPV reduces intestinal inflammation and promotes epithelial healing.

Zinc and Copper

11.  Zinc and immune function: an overview of mechanisms.

Summary: Explains how zinc regulates immunity, wound healing, and antiviral defense.

12.  Copper homeostasis and oxidative stress.

Summary: Reviews the essential role of copper in antioxidant enzyme systems and its balance with zinc.

Tocotrienols (Vitamin E from Annatto)

13.  Tocotrienols: Vitamin E beyond tocopherols.

Summary: Highlights tocotrienols’ superior antioxidant and anti-inflammatory effects compared to common tocopherol forms.

14.  Annatto tocotrienol supplementation improves lipid profile and oxidative stress markers.

Summary: Human study showing improved cholesterol and antioxidant markers after annatto-derived tocotrienol use.

N-Acetyl Cysteine (NAC)

15.  N-acetylcysteine: antioxidant, anti-inflammatory, and mucolytic properties.

Summary: Reviews NAC’s role in glutathione synthesis, detoxification, and reducing oxidative stress.

TMG (Trimethylglycine)

16.  Trimethylglycine (Betaine) in human health and disease.

Summary: Discusses how TMG supports methylation, liver health, and cardiovascular function.